Nemesis Symbiotics^© Treatment

Multiplexed programmable RNA-guided
endonuclease (Symbiotic^©) designed to
inactivate any target genes including
antibiotic resistance genes.

Delivered into the bacterial cell
by Transmids^© or commensal
bacterial conjugation

Expressed within the bacterial
genome to produce guide
RNAs and the endonuclease

Guide RNA linked to
endonuclease provide
target specificity

Symbiotic^© seeks, finds
and inactivates antibiotic
resistance genes and
restores antibiotic sensitivity

Multiplexed programmable RNA-guided
endonuclease (Symbiotic^©) designed to
inactivate any target genes including
antibiotic resistance genes.

Delivered into the bacterial cell
by Transmids^© or commensal
bacterial conjugation

Expressed within the bacterial
genome to produce guide
RNAs and the endonuclease

Guide RNA linked to
endonuclease provide
target specificity

Symbiotic^© seeks, finds
and inactivates antibiotic
resistance genes and
restores antibiotic sensitivity